The Brood Nexus is one of the great mysteries of Hoxxes. While we know for a fact that Glyphids hatch from eggs, these malodorous, organic protuberances nonetheless expel freshly birthed and ravenous Glyphid Swarmers. It's theorized that the Brood Nexus is a completely separate genus, somehow able to replicate the DNA of other species, and use their "designs" for its own protection. Either way, if you meet one, take it out with extreme prejudice.
— Miner's Manual Description
Glyphid Spawn are infantile Glyphids, exclusively spawned by Glyphid Brood Nexuses. While dealing the same amount of damage as Glyphid Swarmers, they are even weaker than their Swarmer counterparts. When the Nexus is destroyed, multiple Spawn explode out (unless the Nexus is frozen). All strategies effective against Swarmers should be even more effective on Spawn.